"Myofibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Spindle-shaped cells with characteristic CONTRACTILE PROTEINS and structures that contribute to the WOUND HEALING process. They occur in GRANULATION TISSUE and also in pathological processes such as FIBROSIS.
| Descriptor ID |
D058628
|
| MeSH Number(s) |
A11.329.228.975 A11.620.520.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Myofibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Myofibroblasts".
This graph shows the total number of publications written about "Myofibroblasts" by people in this website by year, and whether "Myofibroblasts" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 5 | 3 | 8 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 2 | 2 | 4 |
| 2019 | 4 | 1 | 5 |
| 2020 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myofibroblasts" by people in Profiles.
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Critical Role of LMCD1 in Promoting Profibrotic Characteristics of Lung Myofibroblasts in Experimental and Scleroderma-Associated Lung Fibrosis. Arthritis Rheumatol. 2023 03; 75(3):438-448.
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Long noncoding RNA H19X is a key mediator of TGF-?-driven fibrosis. J Clin Invest. 2020 09 01; 130(9):4888-4905.
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Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH. Ann Rheum Dis. 2020 04; 79(4):507-517.
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Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation. Nat Commun. 2019 10 04; 10(1):4509.
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Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019 07; 5(7):eaav3270.
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A Human Skin Model Recapitulates Systemic Sclerosis Dermal Fibrosis and Identifies COL22A1 as a TGF? Early Response Gene that Mediates Fibroblast to Myofibroblast Transition. Genes (Basel). 2019 01 22; 10(2).
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Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis. Basic Res Cardiol. 2019 01 11; 114(2):6.
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Pericytes in the Lung. Adv Exp Med Biol. 2019; 1122:41-58.
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Characterization of human PDGFR-?-positive pericytes from IPF and non-IPF lungs. Am J Physiol Lung Cell Mol Physiol. 2018 12 01; 315(6):L991-L1002.
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Hepatic stellate cells retain retinoid-laden lipid droplets after cellular transdifferentiation into activated myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2018 11 01; 315(5):G713-G721.