"Ataxin-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A deubiquitinating enzyme of the ATAXINS family. It functions in protein homeostasis, GENETIC TRANSCRIPTION; CYTOSKELETON regulation, and MYOGENESIS. CAG TRINUCLEOTIDE REPEAT EXPANSION in the Ataxin-3 gene coding region is associated with spinocerebellar ataxia-3 (MACHADO-JOSEPH DISEASE).
| Descriptor ID |
D000067699
|
| MeSH Number(s) |
D08.811.037.250 D12.776.631.069.875 D12.776.660.075.875
|
| Concept/Terms |
Ataxin-3- Ataxin-3
- Ataxin 3
- SCA3 Protein
- Ataxin-3 Protein
- Ataxin 3 Protein
- Machado-Joseph Disease Protein
- Machado Joseph Disease Protein
- Spinocerebellar Ataxia 3 Protein
- ATXN3 Protein
|
Below are MeSH descriptors whose meaning is more general than "Ataxin-3".
Below are MeSH descriptors whose meaning is more specific than "Ataxin-3".
This graph shows the total number of publications written about "Ataxin-3" by people in this website by year, and whether "Ataxin-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ataxin-3" by people in Profiles.
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The development of hypocretin (orexin) deficiency in hypocretin/ataxin-3 transgenic rats. Neuroscience. 2007 Aug 10; 148(1):34-43.
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Analysis of the role of ubiquitin-interacting motifs in ubiquitin binding and ubiquitylation. J Biol Chem. 2004 Aug 06; 279(32):33528-37.
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Orexin (hypocretin) neurons contain dynorphin. J Neurosci. 2001 Oct 01; 21(19):RC168.