Receptor for Advanced Glycation End Products
"Receptor for Advanced Glycation End Products" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single-pass transmembrane CELL SURFACE RECEPTOR that binds ADVANCED GLYCATION END PRODUCTS to mediate cellular responses to both acute and chronic vascular inflammation in conditions such as ATHEROSCLEROSIS and DIABETES MELLITUS, TYPE 2. It also binds AMYLOID BETA PEPTIDES and the ALARMINS - S100A12 and S100 CALCIUM BINDING PROTEIN BETA SUBUNIT.
Descriptor ID |
D000067759
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MeSH Number(s) |
D12.776.543.750.615
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Concept/Terms |
Receptor for Advanced Glycation End Products- Receptor for Advanced Glycation End Products
- AGE Receptor
- Receptor, AGE
- RAGE (Receptor for Advanced Glycation End Products)
- Advanced Glycosylation End Product Receptors
- Advanced Glycosylation End-Product Receptor
- Advanced Glycosylation End Product Receptor
- Advanced Glycosylation End-Product Receptors
- Advanced Glycosylation Endproduct Receptors
- Receptor for Advanced Glycation End Products (RAGE)
- Receptor for Advanced Glycation Endproducts
- Receptor, Advanced Glycosylation End-Product
- Receptor, Advanced Glycosylation End Product
- Receptor, Advanced Glycosylation End-Products
- Receptor, Advanced Glycosylation End Products
- Advanced Glycosylation End Product-Specific Receptor
- Advanced Glycosylation End Product Specific Receptor
- AGER Protein
- Protein, AGER
- Amphoterin Receptor
- Receptor, Amphoterin
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Below are MeSH descriptors whose meaning is more general than "Receptor for Advanced Glycation End Products".
Below are MeSH descriptors whose meaning is more specific than "Receptor for Advanced Glycation End Products".
This graph shows the total number of publications written about "Receptor for Advanced Glycation End Products" by people in this website by year, and whether "Receptor for Advanced Glycation End Products" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2003 | 0 | 2 | 2 |
2004 | 0 | 2 | 2 |
2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 2 | 2 |
2015 | 1 | 1 | 2 |
2017 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor for Advanced Glycation End Products" by people in Profiles.
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Role and Therapeutic Potential of RAGE Signaling in Neurodegeneration. Curr Drug Targets. 2022; 23(12):1191-1209.
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Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice. Pharmacol Res Perspect. 2020 08; 8(4):e00636.
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Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS. Antioxid Redox Signal. 2018 06 20; 28(18):1587-1602.
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The receptor for advanced glycation end products (RAGE) contributes to the progression of emphysema in mice. PLoS One. 2015; 10(3):e0118979.
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RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment. Cancer Res. 2015 Mar 15; 75(6):974-85.
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Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes pre-eclampsia in Type 1 diabetes. BJOG. 2012 Nov; 119(12):1512-20.
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An aqueous orally active vaccine targeted against a RAGE/AB complex as a novel therapeutic for Alzheimer's disease. Neuromolecular Med. 2012 Jun; 14(2):119-30.
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S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways. Cancer Res. 2012 Feb 01; 72(3):604-15.
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The role of the receptor for advanced glycation end-products in a murine model of silicosis. PLoS One. 2010 Mar 19; 5(3):e9604.
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RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice. EMBO J. 2004 Oct 13; 23(20):4096-105.