"CELF1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1.
| Descriptor ID |
D000067879
|
| MeSH Number(s) |
D12.776.157.725.813.250.500 D12.776.664.962.813.250.500
|
| Concept/Terms |
CELF1 Protein- CELF1 Protein
- Protein, CELF1
- Bruno-Like 2 Protein
- 2 Protein, Bruno-Like
- Bruno Like 2 Protein
- Protein, Bruno-Like 2
- CUGBP, Elav-Like Family Member 1 Protein
- CUGBP, Elav Like Family Member 1 Protein
- CUGBP1 Protein
- Protein, CUGBP1
- BRUNOL2 Protein
- Protein, BRUNOL2
- CUG Triplet Repeat, RNA-Binding Protein 1
- CUG Triplet Repeat, RNA Binding Protein 1
|
Below are MeSH descriptors whose meaning is more general than "CELF1 Protein".
Below are MeSH descriptors whose meaning is more specific than "CELF1 Protein".
This graph shows the total number of publications written about "CELF1 Protein" by people in this website by year, and whether "CELF1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "CELF1 Protein" by people in Profiles.
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Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. PLoS One. 2016; 11(2):e0148717.
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RNA-binding protein CELF1 promotes tumor growth and alters gene expression in oral squamous cell carcinoma. Oncotarget. 2015 Dec 22; 6(41):43620-34.
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Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells. RNA Biol. 2013 Feb; 10(2):277-86.