ETS Motif

"ETS Motif" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A helix-turn-helix motif characterized by three alpha-helices and four-stranded beta-sheets arranged in the order alpha1-beta1-beta2-alpha2-alpha3-beta3-beta4. The third alpha-helix contacts the major groove of DNA. The ETS motif and the flanking amino acid sequences of Ets proteins influence the binding affinity, and the alteration of a single amino acid in the Ets domain can change its DNA binding specificity.

Descriptor ID	D000071419
MeSH Number(s)	G02.111.570.820.709.275.500.360.360.500
Concept/Terms	ETS Motif ETS Motif ETS Motifs Helix-Turn-Helix, ETS-Type Domain Containing Helix Turn Helix, ETS Type Domain Containing ETS Domain ETS Domains

Below are MeSH descriptors whose meaning is more general than "ETS Motif".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Protein Conformation [G02.111.570.820.709]
Protein Structural Elements [G02.111.570.820.709.275]
Amino Acid Motifs [G02.111.570.820.709.275.500]
Helix-Loop-Helix Motifs [G02.111.570.820.709.275.500.360]
Helix-Turn-Helix Motifs [G02.111.570.820.709.275.500.360.360]
ETS Motif [G02.111.570.820.709.275.500.360.360.500]

Below are MeSH descriptors whose meaning is related to "ETS Motif".

Below are MeSH descriptors whose meaning is more specific than "ETS Motif".

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