"NADPH Oxidase 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.
| Descriptor ID |
D000074663
|
| MeSH Number(s) |
D08.811.682.608.575.937 D12.776.331.894.937 D12.776.543.653.937
|
| Concept/Terms |
NADPH Oxidase 4- NADPH Oxidase 4
- Oxidase 4, NADPH
- Renal NAD(P)H Oxidase
- Nox4 Protein
- Renox NAD(P)H Oxidase
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 4".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 4".
This graph shows the total number of publications written about "NADPH Oxidase 4" by people in this website by year, and whether "NADPH Oxidase 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "NADPH Oxidase 4" by people in Profiles.
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NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease. FASEB J. 2020 10; 34(10):13396-13408.
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Cancer-Associated Fibroblasts Promote Immunosuppression by Inducing ROS-Generating Monocytic MDSCs in Lung Squamous Cell Carcinoma. Cancer Immunol Res. 2020 04; 8(4):436-450.
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A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease. J Am Soc Nephrol. 2018 07; 29(7):1917-1927.
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Lysocardiolipin acyltransferase regulates TGF-? mediated lung fibroblast differentiation. Free Radic Biol Med. 2017 11; 112:162-173.
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Transforming growth factor ?1 (TGF?1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis. J Biol Chem. 2017 06 23; 292(25):10490-10519.
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Nox4 contributes to the hypoxia-mediated regulation of actin cytoskeleton in cerebrovascular smooth muscle. Life Sci. 2016 Oct 15; 163:46-54.
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Mechanisms of bradykinin-induced expression of connective tissue growth factor and nephrin in podocytes. Am J Physiol Renal Physiol. 2015 Dec 01; 309(11):F980-90.
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Minocycline reduces spontaneous hemorrhage in mouse models of cerebral amyloid angiopathy. Stroke. 2015 Jun; 46(6):1633-1640.
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The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosis. Free Radic Biol Med. 2013 Aug; 61:26-39.
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Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells. Free Radic Biol Med. 2010 Jan 15; 48(2):348-56.