"Interferon-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity.
| Descriptor ID |
D016899
|
| MeSH Number(s) |
D12.644.276.374.440.890.275 D12.776.467.374.440.890.275 D23.529.374.440.890.275
|
| Concept/Terms |
Interferon-beta- Interferon-beta
- Interferon beta
- Interferon, Fibroblast
- Fibroblast Interferon
- Interferon, beta
- beta Interferon
- beta-Interferon
beta-1 Interferon- beta-1 Interferon
- beta 1 Interferon
- Interferon-beta1
- Interferon beta1
- Interferon, beta-1
- Interferon, beta 1
|
Below are MeSH descriptors whose meaning is more general than "Interferon-beta".
Below are MeSH descriptors whose meaning is more specific than "Interferon-beta".
This graph shows the total number of publications written about "Interferon-beta" by people in this website by year, and whether "Interferon-beta" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon-beta" by people in Profiles.
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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling. Immunity. 2020 04 14; 52(4):668-682.e7.
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Rational design of glycoengineered interferon-? analogs with improved aggregation state: experimental validation. Protein Eng Des Sel. 2017 Jan; 30(1):23-30.
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Type I IFN promotes IL-10 production from T cells to suppress Th17 cells and Th17-associated autoimmune inflammation. PLoS One. 2011; 6(12):e28432.
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Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor. J Biol Chem. 2011 Jun 24; 286(25):22069-76.
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A comparison of the natural history and outcome of treatment for Asian and non-Asian hepatitis C-infected patients. J Viral Hepat. 2011 Jul; 18(7):e270-7.
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NF-kappaB activation mediates resistance to IFN beta in MLL-rearranged acute lymphoblastic leukemia. Leukemia. 2010 Apr; 24(4):806-12.
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Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor. J Biol Chem. 2010 Jan 22; 285(4):2318-25.
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Human cancer cells have specifically lost the ability to induce the synergistic state caused by tumor necrosis factor plus interferon-beta. Cytokine. 2009 Sep; 47(3):199-205.
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The addition of tumor necrosis factor plus beta interferon induces a novel synergistic antiviral state against poxviruses in primary human fibroblasts. J Virol. 2009 Jan; 83(2):498-511.
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RIG-I mediates the co-induction of tumor necrosis factor and type I interferon elicited by myxoma virus in primary human macrophages. PLoS Pathog. 2008 Jul 11; 4(7):e1000099.