Tumor Necrosis Factor-alpha
"Tumor Necrosis Factor-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
| Descriptor ID |
D014409
|
| MeSH Number(s) |
D12.644.276.374.500.800 D12.644.276.374.750.626 D12.776.124.900 D12.776.395.930 D12.776.467.374.500.800 D12.776.467.374.750.626 D23.529.374.500.800 D23.529.374.750.626
|
| Concept/Terms |
Tumor Necrosis Factor-alpha- Tumor Necrosis Factor-alpha
- Tumor Necrosis Factor alpha
- Cachectin
- Cachectin-Tumor Necrosis Factor
- Cachectin Tumor Necrosis Factor
- Tumor Necrosis Factor Ligand Superfamily Member 2
- Tumor Necrosis Factor
- TNF Superfamily, Member 2
- TNFalpha
- TNF-alpha
|
Below are MeSH descriptors whose meaning is more general than "Tumor Necrosis Factor-alpha".
Below are MeSH descriptors whose meaning is more specific than "Tumor Necrosis Factor-alpha".
This graph shows the total number of publications written about "Tumor Necrosis Factor-alpha" by people in this website by year, and whether "Tumor Necrosis Factor-alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 7 | 1 | 8 |
| 1995 | 5 | 1 | 6 |
| 1996 | 8 | 6 | 14 |
| 1997 | 8 | 3 | 11 |
| 1998 | 8 | 8 | 16 |
| 1999 | 6 | 8 | 14 |
| 2000 | 4 | 8 | 12 |
| 2001 | 9 | 10 | 19 |
| 2002 | 8 | 8 | 16 |
| 2003 | 8 | 12 | 20 |
| 2004 | 11 | 12 | 23 |
| 2005 | 12 | 8 | 20 |
| 2006 | 7 | 18 | 25 |
| 2007 | 3 | 14 | 17 |
| 2008 | 9 | 14 | 23 |
| 2009 | 8 | 9 | 17 |
| 2010 | 6 | 16 | 22 |
| 2011 | 9 | 9 | 18 |
| 2012 | 2 | 13 | 15 |
| 2013 | 5 | 12 | 17 |
| 2014 | 5 | 3 | 8 |
| 2015 | 4 | 13 | 17 |
| 2016 | 2 | 9 | 11 |
| 2017 | 2 | 10 | 12 |
| 2018 | 5 | 4 | 9 |
| 2019 | 0 | 10 | 10 |
| 2020 | 4 | 1 | 5 |
| 2021 | 1 | 4 | 5 |
| 2022 | 1 | 2 | 3 |
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Below are the most recent publications written about "Tumor Necrosis Factor-alpha" by people in Profiles.
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Melanoma risk during immunomodulating treatment. Melanoma Res. 2022 12 01; 32(6):411-418.
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CD44 receptor targeted nanoparticles augment immunity against tuberculosis in mice. J Control Release. 2022 09; 349:796-811.
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TNF blockade enhances the efficacy of myxoma virus-based oncolytic virotherapy. J Immunother Cancer. 2022 05; 10(5).
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Sociodemographic factors affecting perceived stress during pregnancy and the association with immune-mediator concentrations. J Perinat Med. 2022 Feb 23; 50(2):192-199.
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Cytokine Signaling and Matrix Remodeling Pathways Associated with Cardiac Sarcoidosis Disease Activity Defined Using FDG PET Imaging. Int Heart J. 2021 Sep 30; 62(5):1096-1105.
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Evidence for ceramide induced cytotoxicity in retinal ganglion cells. Exp Eye Res. 2021 10; 211:108762.
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A Milk-Fat Based Diet Increases Metastasis in the MMTV-PyMT Mouse Model of Breast Cancer. Nutrients. 2021 Jul 15; 13(7).
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Ceramide kinase regulates TNF-a-induced immune responses in human monocytic cells. Sci Rep. 2021 04 15; 11(1):8259.
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Cytotrophoblasts suppress macrophage-mediated inflammation through a contact-dependent mechanism. Am J Reprod Immunol. 2021 03; 85(3):e13352.
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Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-a. Sci Rep. 2020 10 08; 10(1):16802.