Transcription Factor CHOP
"Transcription Factor CHOP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CCAAT-enhancer binding protein that is induced by DNA DAMAGE and growth arrest. It serves as a dominant negative inhibitor of other CCAAT-enhancer binding proteins.
| Descriptor ID |
D051742
|
| MeSH Number(s) |
D12.776.260.108.124.875 D12.776.660.167.875 D12.776.930.127.124.875
|
| Concept/Terms |
Transcription Factor CHOP- Transcription Factor CHOP
- CHOP, Transcription Factor
- Growth Arrest And DNA Damage-Inducible Protein 153
- Growth Arrest And DNA Damage Inducible Protein 153
- DNA Damage-Inducible Transcript 3 Protein
- DNA Damage Inducible Transcript 3 Protein
- GADD153 Protein
- C-EBP Homologous Protein
- C EBP Homologous Protein
- Homologous Protein, C-EBP
- DDIT3 Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor CHOP".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor CHOP".
This graph shows the total number of publications written about "Transcription Factor CHOP" by people in this website by year, and whether "Transcription Factor CHOP" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 4 | 4 |
| 2017 | 2 | 1 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factor CHOP" by people in Profiles.
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Coordination of the unfolded protein response during hepatic steatosis identifies CHOP as a specific regulator of hepatocyte ballooning. Cell Stress Chaperones. 2020 11; 25(6):969-978.
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Fumarate and oxidative stress synergize to promote stability of C/EBP homologous protein in the adipocyte. Free Radic Biol Med. 2020 02 20; 148:70-82.
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ER stress-induced mediator C/EBP homologous protein thwarts effector T?cell activity in tumors through T-bet repression. Nat Commun. 2019 03 20; 10(1):1280.
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CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response. Nat Struct Mol Biol. 2017 Oct; 24(10):834-839.
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Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes. Antioxid Redox Signal. 2017 Dec 01; 27(16):1281-1296.
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Modulation of Pancreatic Islets' Function and Survival During Aging Involves the Differential Regulation of Endoplasmic Reticulum Stress by p21 and CHOP. Antioxid Redox Signal. 2017 08 01; 27(4):185-200.
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A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. PLoS One. 2016; 11(12):e0167979.
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Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy. Diabetologia. 2016 10; 59(10):2251-61.
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Endoplasmic reticulum stress is associated with the pathogenesis of pemphigus vulgaris. Exp Dermatol. 2016 09; 25(9):731-3.
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TULP1 Missense Mutations Induces the Endoplasmic Reticulum Unfolded Protein Response Stress Complex (ER-UPR). Adv Exp Med Biol. 2016; 854:223-30.