"Sphingosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
| Descriptor ID |
D013110
|
| MeSH Number(s) |
D02.033.100.700 D02.033.455.843 D02.092.063.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sphingosine".
Below are MeSH descriptors whose meaning is more specific than "Sphingosine".
This graph shows the total number of publications written about "Sphingosine" by people in this website by year, and whether "Sphingosine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 1 | 3 |
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 2 | 5 |
| 1998 | 1 | 2 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 3 | 1 | 4 |
| 2001 | 4 | 0 | 4 |
| 2002 | 3 | 1 | 4 |
| 2003 | 3 | 0 | 3 |
| 2004 | 2 | 1 | 3 |
| 2005 | 3 | 3 | 6 |
| 2006 | 10 | 5 | 15 |
| 2007 | 7 | 6 | 13 |
| 2008 | 1 | 7 | 8 |
| 2009 | 2 | 4 | 6 |
| 2010 | 6 | 6 | 12 |
| 2011 | 7 | 5 | 12 |
| 2012 | 5 | 6 | 11 |
| 2013 | 6 | 7 | 13 |
| 2014 | 4 | 1 | 5 |
| 2015 | 4 | 5 | 9 |
| 2016 | 3 | 1 | 4 |
| 2017 | 6 | 2 | 8 |
| 2018 | 5 | 4 | 9 |
| 2019 | 2 | 2 | 4 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sphingosine" by people in Profiles.
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Upregulation of sphingosine kinase 1 in response to doxorubicin generates an angiogenic response via stabilization of Snail. FASEB J. 2023 03; 37(3):e22787.
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A simple, highly sensitive, and facile method to quantify ceramide at the plasma membrane. J Lipid Res. 2023 02; 64(2):100322.
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Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients. Sci Rep. 2021 07 09; 11(1):14232.
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Bioactive sphingolipids: Advancements and contributions from the laboratory of Dr. Lina M. Obeid. Cell Signal. 2021 03; 79:109875.
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Maternal and fetal alkaline ceramidase 2 is required for placental vascular integrity in mice. FASEB J. 2020 11; 34(11):15252-15268.
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Ceramide and Sphingosine Regulation of Myelinogenesis: Targeting Serine Palmitoyltransferase Using microRNA in Multiple Sclerosis. Int J Mol Sci. 2019 Oct 11; 20(20).
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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity. Cell Rep. 2019 08 13; 28(7):1879-1893.e7.
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Differences in plasma levels of long chain and very long chain ceramides between African Americans and whites: An observational study. PLoS One. 2019; 14(5):e0216213.
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Bioactive sphingolipid profile in a xenograft mouse model of head and neck squamous cell carcinoma. PLoS One. 2019; 14(4):e0215770.
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Neutral ceramidase: Advances in mechanisms, cell regulation, and roles in cancer. Adv Biol Regul. 2019 01; 71:141-146.