"Quinine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
| Descriptor ID |
D011803
|
| MeSH Number(s) |
D03.132.206.719 D03.605.687.762 D03.633.100.810.762
|
| Concept/Terms |
Quinine Sulfate- Quinine Sulfate
- Sulfate, Quinine
- Quinine Sulphate
- Sulphate, Quinine
|
Below are MeSH descriptors whose meaning is more general than "Quinine".
Below are MeSH descriptors whose meaning is more specific than "Quinine".
This graph shows the total number of publications written about "Quinine" by people in this website by year, and whether "Quinine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Quinine" by people in Profiles.
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Absence of compulsive drinking phenotype in adult male rats exposed to ethanol in a binge-like pattern during adolescence. Alcohol. 2019 09; 79:93-103.
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Alteration of the Disposition of Quinine in Healthy Volunteers After Concurrent Ciprofloxacin Administration. Am J Ther. 2016 Mar-Apr; 23(2):e398-404.
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Effect of dehusked Garcinia kola seeds on the overall pharmacokinetics of quinine in healthy Nigerian volunteers. J Clin Pharmacol. 2015 Mar; 55(3):348-54.
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Bitter taste inhibiting agents for whey protein hydrolysate and whey protein hydrolysate beverages. J Food Sci. 2012 Aug; 77(8):S282-7.
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The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex. J Inorg Biochem. 2011 Mar; 105(3):467-75.
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Quinine and chloroquine differentially perturb heme monomer-dimer equilibrium. Inorg Chem. 2008 Jul 07; 47(13):6077-81.
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Drug-induced thrombotic microangiopathy. Semin Thromb Hemost. 2005 Dec; 31(6):681-90.
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Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution. Inorg Chem. 2004 Dec 13; 43(25):8078-84.