"Quinidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
| Descriptor ID |
D011802
|
| MeSH Number(s) |
D03.132.206.636 D03.605.687.637 D03.633.100.810.699
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Quinidine".
Below are MeSH descriptors whose meaning is more specific than "Quinidine".
This graph shows the total number of publications written about "Quinidine" by people in this website by year, and whether "Quinidine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Quinidine" by people in Profiles.
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Across state lines: Fulminant Babesia microti infection in a liver transplant recipient. Transpl Infect Dis. 2017 Oct; 19(5).
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Alteration of the Disposition of Quinine in Healthy Volunteers After Concurrent Ciprofloxacin Administration. Am J Ther. 2016 Mar-Apr; 23(2):e398-404.
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Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial. JAMA. 2015 Sep 22-29; 314(12):1242-54.
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Effect of dehusked Garcinia kola seeds on the overall pharmacokinetics of quinine in healthy Nigerian volunteers. J Clin Pharmacol. 2015 Mar; 55(3):348-54.
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Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution. Inorg Chem. 2004 Dec 13; 43(25):8078-84.
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Single-dose pharmacokinetics of methylphenidate in CYP2D6 extensive and poor metabolizers. J Clin Psychopharmacol. 2000 Jun; 20(3):347-9.
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Pediatric ECMO for severe quinidine cardiotoxicity. Pediatr Emerg Care. 1997 Apr; 13(2):111-3.
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Possible pharmacokinetic interaction with quinidine: ciprofloxacin or metronidazole? Ann Pharmacother. 1996 Apr; 30(4):364-6.
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Ventricular tachydysrhythmias in near-miss sudden infant death syndrome. Am Heart J. 1986 Feb; 111(2):398-400.
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Flecainide: a new prototype antiarrhythmic agent. Pharmacotherapy. 1985 Jul-Aug; 5(4):209-21.