"G-Quadruplexes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)
| Descriptor ID |
D054856
|
| MeSH Number(s) |
G02.111.570.820.486.550 G05.360.580.550
|
| Concept/Terms |
G-Quadruplexes- G-Quadruplexes
- G Quadruplexes
- Guanine-Quadruplexes
- Guanine Quadruplexes
Guanine-Tetrads- Guanine-Tetrads
- Guanine Tetrads
- Guanine-Tetrad
- Guanine-Quartets
- Guanine Quartets
- Guanine-Quartet
G-Quadruplexes, DNA- G-Quadruplexes, DNA
- G Quadruplexes, DNA
- Tetraplex DNA
- DNA, Tetraplex
- DNA G-Quadruplexes
- DNA G Quadruplexes
- DNA, Quadruplex
- Quadruplex DNA
G-Quadruplexes, RNA- G-Quadruplexes, RNA
- G Quadruplexes, RNA
- RNA G-Quadruplexes
- RNA, G-Quadruplexes
- G-Quadruplexes RNA
- G-Quadruplexes RNAs
- RNA, G Quadruplexes
- RNAs, G-Quadruplexes
|
Below are MeSH descriptors whose meaning is more general than "G-Quadruplexes".
Below are MeSH descriptors whose meaning is more specific than "G-Quadruplexes".
This graph shows the total number of publications written about "G-Quadruplexes" by people in this website by year, and whether "G-Quadruplexes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 3 | 0 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "G-Quadruplexes" by people in Profiles.
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Small-Molecule-Targeting Hairpin Loop of hTERT Promoter G-Quadruplex Induces Cancer Cell Death. Cell Chem Biol. 2019 08 15; 26(8):1110-1121.e4.
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Targeting C-myc G-quadruplex: dual recognition by aminosugar-bisbenzimidazoles with varying linker lengths. Molecules. 2013 Nov 18; 18(11):14228-40.
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An assay for human telomeric G-quadruplex DNA binding drugs. Bioorg Med Chem Lett. 2013 Dec 15; 23(24):6695-9.
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Dual recognition of the human telomeric G-quadruplex by a neomycin-anthraquinone conjugate. Chem Commun (Camb). 2013 Jun 28; 49(51):5796-8.
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Synthesis and spectroscopic studies of the aminoglycoside (neomycin)--perylene conjugate binding to human telomeric DNA. Biochemistry. 2011 Apr 12; 50(14):2838-49.