"Aptamers, Nucleotide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
| Descriptor ID |
D052157
|
| MeSH Number(s) |
D13.695.578.424.224
|
| Concept/Terms |
RNA Aptamers- RNA Aptamers
- Aptamers, RNA
- Oligonucleotide Ligands, RNA
- RNA Oligonucleotide Ligands
DNA Aptamers- DNA Aptamers
- Aptamers, DNA
- Oligonucleotide Ligands, DNA
- DNA Oligonucleotide Ligands
|
Below are MeSH descriptors whose meaning is more general than "Aptamers, Nucleotide".
Below are MeSH descriptors whose meaning is more specific than "Aptamers, Nucleotide".
This graph shows the total number of publications written about "Aptamers, Nucleotide" by people in this website by year, and whether "Aptamers, Nucleotide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aptamers, Nucleotide" by people in Profiles.
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RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers. RNA. 2020 08; 26(8):982-995.
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Facile supermolecular aptamer inhibitors of L-selectin. PLoS One. 2015; 10(3):e0123034.
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In search of novel drug target sites on estrogen receptors using RNA aptamers. Nucleic Acid Ther. 2014 Jun; 24(3):226-38.
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A polyvalent aptamer system for targeted drug delivery. Biomaterials. 2013 Dec; 34(37):9728-35.
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Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer. Biomaterials. 2013 Jul; 34(21):5244-53.
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Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection. ACS Nano. 2012 Jan 24; 6(1):696-704.
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First clinical application of an actively reversible direct factor IXa inhibitor as an anticoagulation strategy in patients undergoing percutaneous coronary intervention. Circulation. 2010 Aug 10; 122(6):614-22.
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Mechanism of regulation of bcl-2 mRNA by nucleolin and A+U-rich element-binding factor 1 (AUF1). J Biol Chem. 2010 Aug 27; 285(35):27182-27191.
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Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells. Mol Pharmacol. 2009 Nov; 76(5):984-91.
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Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy. ChemMedChem. 2008 Sep; 3(9):1311-5.