Phosphorothioate Oligonucleotides
"Phosphorothioate Oligonucleotides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Modified oligonucleotides in which one of the oxygens of the phosphate group is replaced with a sulfur atom.
| Descriptor ID |
D054735
|
| MeSH Number(s) |
D13.695.578.424.575
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphorothioate Oligonucleotides".
Below are MeSH descriptors whose meaning is more specific than "Phosphorothioate Oligonucleotides".
This graph shows the total number of publications written about "Phosphorothioate Oligonucleotides" by people in this website by year, and whether "Phosphorothioate Oligonucleotides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphorothioate Oligonucleotides" by people in Profiles.
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Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect. ACS Chem Biol. 2021 02 19; 16(2):334-343.
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Efficient stabilization of phosphodiester (PO), phosphorothioate (PS), and 2'-O-methoxy (2'-OMe) DNA?RNA hybrid duplexes by amino sugars. Biochemistry. 2012 Jul 10; 51(27):5496-505.