Actin Depolymerizing Factors
"Actin Depolymerizing Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
| Descriptor ID |
D051339
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| MeSH Number(s) |
D05.750.078.730.212 D12.776.220.525.212
|
| Concept/Terms |
Actin Depolymerizing Factors- Actin Depolymerizing Factors
- Depolymerizing Factors, Actin
- Cofilins
- Cofilin Proteins
- Actin Depolymerizing Proteins
- Depolymerizing Proteins, Actin
- ADF Proteins (Actin Depolymerizing Factors)
|
Below are MeSH descriptors whose meaning is more general than "Actin Depolymerizing Factors".
Below are MeSH descriptors whose meaning is more specific than "Actin Depolymerizing Factors".
This graph shows the total number of publications written about "Actin Depolymerizing Factors" by people in this website by year, and whether "Actin Depolymerizing Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Actin Depolymerizing Factors" by people in Profiles.
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Relapse-Associated Transient Synaptic Potentiation Requires Integrin-Mediated Activation of Focal Adhesion Kinase and Cofilin in D1-Expressing Neurons. J Neurosci. 2020 10 28; 40(44):8463-8477.
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Phosphorylated cofilin-2 is more prone to oxidative modifications on Cys39 and favors amyloid fibril formation. Redox Biol. 2020 10; 37:101691.
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Post-translational S-glutathionylation of cofilin increases actin cycling during cocaine seeking. PLoS One. 2019; 14(9):e0223037.
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Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 03 04; 9(1):3357.
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Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics. Sci Signal. 2016 Apr 19; 9(424):rs3.
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Stress-induced sensitization to cocaine: actin cytoskeleton remodeling within mesocorticolimbic nuclei. Eur J Neurosci. 2012 Oct; 36(8):3103-17.
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Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation. J Immunol. 2011 Dec 01; 187(11):5887-900.