"Cell Degranulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of losing secretory granules (SECRETORY VESICLES). This occurs, for example, in mast cells, basophils, neutrophils, eosinophils, and platelets when secretory products are released from the granules by EXOCYTOSIS.
| Descriptor ID |
D015550
|
| MeSH Number(s) |
G04.468.160
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cell Degranulation".
Below are MeSH descriptors whose meaning is more specific than "Cell Degranulation".
This graph shows the total number of publications written about "Cell Degranulation" by people in this website by year, and whether "Cell Degranulation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cell Degranulation" by people in Profiles.
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Inhibition of MRGPRX2 but not FceRI or MrgprB2-mediated mast cell degranulation by a small molecule inverse receptor agonist. Front Immunol. 2022; 13:1033794.
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Lactic acid suppresses MRGPRX2 mediated mast cell responses. Cell Immunol. 2021 10; 368:104422.
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MRGPRX2 Activation by Rocuronium: Insights from Studies with Human Skin Mast Cells and Missense Variants. Cells. 2021 01 15; 10(1).
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Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses. Front Immunol. 2020; 11:703.
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Silver nanoparticle immunomodulatory potential in absence of direct cytotoxicity in RAW 264.7 macrophages and MPRO 2.1 neutrophils. J Immunotoxicol. 2019 12; 16(1):63-73.
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Neutrophil proteome shifts over the myocardial infarction time continuum. Basic Res Cardiol. 2019 08 15; 114(5):37.
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Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Ra Complexes Enhances Tumor Control. Cancer Immunol Res. 2019 08; 7(8):1371-1380.
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Contribution of engineered nanomaterials physicochemical properties to mast cell degranulation. Sci Rep. 2017 03 06; 7:43570.
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NK Cell and Ig Interplay in Defense against Herpes Simplex Virus Type 1: Epistatic Interaction of CD16A and IgG1 Allotypes of Variable Affinities Modulates Antibody-Dependent Cellular Cytotoxicity and Susceptibility to Clinical Reactivation. J Immunol. 2015 Aug 15; 195(4):1676-84.
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Influence of physicochemical properties of silver nanoparticles on mast cell activation and degranulation. Toxicol In Vitro. 2015 Feb; 29(1):195-203.