"Kupffer Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized phagocytic cells of the MONONUCLEAR PHAGOCYTE SYSTEM found on the luminal surface of the hepatic sinusoids. They filter bacteria and small foreign proteins out of the blood, and dispose of worn out red blood cells.
| Descriptor ID |
D007728
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| MeSH Number(s) |
A11.329.372.588 A11.627.482.588 A11.733.397.588 A15.382.680.397.588 A15.382.812.522.588
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Kupffer Cells".
Below are MeSH descriptors whose meaning is more specific than "Kupffer Cells".
This graph shows the total number of publications written about "Kupffer Cells" by people in this website by year, and whether "Kupffer Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 7 | 0 | 7 |
| 1995 | 3 | 2 | 5 |
| 1996 | 2 | 2 | 4 |
| 1997 | 3 | 1 | 4 |
| 1998 | 3 | 2 | 5 |
| 1999 | 2 | 2 | 4 |
| 2000 | 2 | 1 | 3 |
| 2001 | 3 | 0 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Kupffer Cells" by people in Profiles.
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Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21. Am J Physiol Gastrointest Liver Physiol. 2019 10 01; 317(4):G408-G428.
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Characterization of changes in intrahepatic immune cell populations during HCV treatment with sofosbuvir and ribavirin. J Viral Hepat. 2019 03; 26(3):323-328.
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Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. Am J Physiol Gastrointest Liver Physiol. 2016 04 01; 310(7):G510-25.
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M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling. Diabetes. 2015 Aug; 64(8):2836-46.
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Intereukin-10 and Kupffer cells protect steatotic mice livers from ischemia-reperfusion injury. Eur Cytokine Netw. 2014 Oct-Dec; 25(4):69-76.
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Toll-like receptor 4 knockout mice are protected from endothelial overactivation in the absence of Kupffer cells after total hepatic ischemia/reperfusion. Liver Transpl. 2011 Sep; 17(9):1089-98.
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Prolonged hepatomegaly in mice that cannot inactivate bacterial endotoxin. Hepatology. 2011 Sep 02; 54(3):1051-62.
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Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10. J Immunol. 2010 May 15; 184(10):5849-58.
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Organogenesis and development of the liver. Dev Cell. 2010 Feb 16; 18(2):175-89.
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A host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen. J Biol Chem. 2007 May 04; 282(18):13726-35.