Son of Sevenless Proteins
"Son of Sevenless Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS that are genetically related to the Son of Sevenless gene from DROSOPHILA. Sevenless refers to genetic mutations in DROSOPHILA that cause loss of the R7 photoreceptor which is required to see UV light.
| Descriptor ID |
D020664
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| MeSH Number(s) |
D12.644.360.325.300.700.700 D12.776.476.325.300.700.700
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Son of Sevenless Proteins".
Below are MeSH descriptors whose meaning is more specific than "Son of Sevenless Proteins".
This graph shows the total number of publications written about "Son of Sevenless Proteins" by people in this website by year, and whether "Son of Sevenless Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Son of Sevenless Proteins" by people in Profiles.
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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol. 2017 Mar; 28(3):981-994.
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Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway. Nature. 1995 Aug 31; 376(6543):781-4.
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B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein. J Immunol. 1994 Jul 15; 153(2):623-36.