Catechol O-Methyltransferase
"Catechol O-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme that catalyzes the movement of a methyl group from S-adenosylmethionone to a catechol or a catecholamine.
| Descriptor ID |
D002394
|
| MeSH Number(s) |
D08.811.913.555.500.250
|
| Concept/Terms |
Catechol O-Methyltransferase- Catechol O-Methyltransferase
- O-Methyltransferase, Catechol
- Catechol-O-Methyltransferase
- Catechol O Methyltransferase
- Catechol Methyltransferase
- Methyltransferase, Catechol
|
Below are MeSH descriptors whose meaning is more general than "Catechol O-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Catechol O-Methyltransferase".
This graph shows the total number of publications written about "Catechol O-Methyltransferase" by people in this website by year, and whether "Catechol O-Methyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2011 | 2 | 0 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Catechol O-Methyltransferase" by people in Profiles.
-
Effects of pharmacological and genetic regulation of COMT activity in alcohol use disorder: a randomized, placebo-controlled trial of tolcapone. Neuropsychopharmacology. 2022 10; 47(11):1953-1960.
-
Computational analysis of deleterious single nucleotide polymorphisms in catechol O-Methyltransferase conferring risk to post-traumatic stress disorder. J Psychiatr Res. 2021 06; 138:207-218.
-
Opioid and Dopamine Genes Interact to Predict Naltrexone Response in a Randomized Alcohol Use Disorder Clinical Trial. Alcohol Clin Exp Res. 2020 10; 44(10):2084-2096.
-
Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial. Neuropsychopharmacology. 2018 05; 43(6):1247-1256.
-
Binge-Like Alcohol Exposure During Adolescence Disrupts Dopaminergic Neurotransmission in the Adult Prelimbic Cortex. Neuropsychopharmacology. 2017 Apr; 42(5):1024-1036.
-
COMT val158met moderation of dopaminergic drug effects on cognitive function: a critical review. Pharmacogenomics J. 2016 10; 16(5):430-8.
-
Genetic associations with performance on a behavioral measure of distress intolerance. J Psychiatr Res. 2012 Jan; 46(1):87-94.
-
Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations. Am J Med Genet B Neuropsychiatr Genet. 2011 Sep; 156B(6):651-60.
-
Adolescent cannabis use increases risk for cocaine-induced paranoia. Drug Alcohol Depend. 2010 Mar 01; 107(2-3):196-201.
-
Association between COMT, PTSD, and increased smoking following hurricane exposure in an epidemiologic sample. Psychiatry. 2009; 72(4):360-9.