Silent Information Regulator Proteins, Saccharomyces cerevisiae
"Silent Information Regulator Proteins, Saccharomyces cerevisiae" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. They mediate the formation of silenced CHROMATIN and repress both transcription and recombination at other loci as well. They are comprised of 4 non-homologous, interacting proteins, Sir1p, Sir2p, Sir3p, and Sir4p. Sir2p, an NAD-dependent HISTONE DEACETYLASE, is the founding member of the family of SIRTUINS.
| Descriptor ID |
D038281
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| MeSH Number(s) |
D12.776.354.750.750 D12.776.660.820
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| Concept/Terms |
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This graph shows the total number of publications written about "Silent Information Regulator Proteins, Saccharomyces cerevisiae" by people in this website by year, and whether "Silent Information Regulator Proteins, Saccharomyces cerevisiae" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Silent Information Regulator Proteins, Saccharomyces cerevisiae" by people in Profiles.
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Mechanism of Regulation of Intrachromatid Recombination and Long-Range Chromosome Interactions in Saccharomyces cerevisiae. Mol Cell Biol. 2016 05 15; 36(10):1451-63.
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Nicotinamide induces Fob1-dependent plasmid integration into chromosome XII in Saccharomyces cerevisiae. FEMS Yeast Res. 2012 Dec; 12(8):949-57.
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Replication fork arrest and rDNA silencing are two independent and separable functions of the replication terminator protein Fob1 of Saccharomyces cerevisiae. J Biol Chem. 2010 Apr 23; 285(17):12612-9.