"Hyperinsulinism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
Descriptor ID |
D006946
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MeSH Number(s) |
C18.452.394.968
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hyperinsulinism".
Below are MeSH descriptors whose meaning is more specific than "Hyperinsulinism".
This graph shows the total number of publications written about "Hyperinsulinism" by people in this website by year, and whether "Hyperinsulinism" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 1 | 2 |
1997 | 0 | 1 | 1 |
1998 | 1 | 1 | 2 |
1999 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
2003 | 1 | 0 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 2 | 2 |
2007 | 1 | 1 | 2 |
2008 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hyperinsulinism" by people in Profiles.
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Metabolic syndrome exacerbates inflammation and bone loss in periodontitis. J Dent Res. 2015 Feb; 94(2):362-70.
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Insulin resistance and metabolic hepatocarcinogenesis with parent-of-origin effects in A?B mice. Am J Pathol. 2011 Dec; 179(6):2855-65.
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Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes. J Immunol. 2008 Dec 15; 181(12):8323-34.
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The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Endocrine. 2007 Feb; 31(1):5-17.
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Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways. Endocrinology. 2007 May; 148(5):2016-26.
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The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. J Clin Invest. 2005 Apr; 115(4):1006-15.
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Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells. J Neurosci. 2005 Feb 02; 25(5):1240-8.
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National Cholesterol Education Program versus World Health Organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study. Circulation. 2004 Sep 07; 110(10):1251-7.
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Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats. Hypertension. 2003 Nov; 42(5):1026-33.
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Analysis of obesity and hyperinsulinemia in the development of metabolic syndrome: San Antonio Heart Study. Obes Res. 2002 Sep; 10(9):923-31.