"Lomustine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkylating agent of value against both hematologic malignancies and solid tumors.
| Descriptor ID |
D008130
|
| MeSH Number(s) |
D02.654.692.440 D02.948.594.440
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lomustine".
Below are MeSH descriptors whose meaning is more specific than "Lomustine".
This graph shows the total number of publications written about "Lomustine" by people in this website by year, and whether "Lomustine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lomustine" by people in Profiles.
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Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial. JAMA Oncol. 2020 12 01; 6(12):1939-1946.
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Comprehensive Genomic Analysis in NRG Oncology/RTOG 9802: A Phase III Trial of Radiation Versus Radiation Plus Procarbazine, Lomustine (CCNU), and Vincristine in High-Risk Low-Grade Glioma. J Clin Oncol. 2020 10 10; 38(29):3407-3417.
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Sister chromatid exchange induction near the baseline with low doses of the alkylating agent CCNU. Environ Mol Mutagen. 1988; 12(2):209-17.
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Sister chromatid exchange in human lymphocytes exposed to ascorbic acid and the cancer chemotherapeutic agent 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Teratog Carcinog Mutagen. 1988; 8(6):339-46.
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A comparative analysis of drug-induced DNA effects in a nitrogen mustard resistant cell line expressing sensitivity to nitrosoureas. Biochem Pharmacol. 1986 Apr 01; 35(7):1171-6.
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Alkylating agent interactions with the nuclear matrix. Biochem Pharmacol. 1983 Dec 01; 32(23):3509-16.
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Repair of DNA alkylation induced in L1210 leukemia and murine bone marrow by three chloroethylnitrosoureas. Cancer Res. 1982 Jul; 42(7):2605-8.
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Nitrosourea interaction with chromatin and effect on poly(adenosine diphosphate ribose) polymerase activity. Cancer Res. 1979 Apr; 39(4):1411-7.
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Binding of chlorozotocin and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea to chromatin and nucleosomal fractions of HeLa cells. Cancer Res. 1978 Oct; 38(10):3371-8.
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Current status of the therapy of advanced renal carcinoma. J Surg Oncol. 1977; 9(3):277-88.