"Nimustine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agents or with radiotherapy for the treatment of various neoplasms.
Descriptor ID |
D015376
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MeSH Number(s) |
D02.654.692.550 D02.948.594.550
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nimustine".
Below are MeSH descriptors whose meaning is more specific than "Nimustine".
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Below are the most recent publications written about "Nimustine" by people in Profiles.
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Determinants of drug response in a cisplatin-resistant human lung cancer cell line. Jpn J Cancer Res. 1990 May; 81(5):527-35.