Guanylyl Imidodiphosphate
"Guanylyl Imidodiphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.
| Descriptor ID |
D006165
|
| MeSH Number(s) |
D03.633.100.759.646.454.504.400 D13.695.667.454.504.400 D13.695.827.426.504.400
|
| Concept/Terms |
Guanylyl Imidodiphosphate- Guanylyl Imidodiphosphate
- Imidodiphosphate, Guanylyl
- Guanosine 5'-(Beta,Gamma-Imido)Triphosphate
- Guanyl-5'-Imidodiphosphate
- Guanyl 5' Imidodiphosphate
- GMP-PNP
- P(NH)PPG
- GMP-P(NH)P
- Gpp(NH)p
|
Below are MeSH descriptors whose meaning is more general than "Guanylyl Imidodiphosphate".
Below are MeSH descriptors whose meaning is more specific than "Guanylyl Imidodiphosphate".
This graph shows the total number of publications written about "Guanylyl Imidodiphosphate" by people in this website by year, and whether "Guanylyl Imidodiphosphate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 3 | 3 |
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanylyl Imidodiphosphate" by people in Profiles.
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Analysis of signal transfer from receptor to Go/Gi in different membrane environments and receptor-independent activators of brain G protein. Methods Enzymol. 2002; 344:140-52.
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Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits. J Biol Chem. 1995 Aug 04; 270(31):18691-9.
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Lack of discrimination by agonists for D2 and D3 dopamine receptors. Neuropsychopharmacology. 1995 Jul; 12(4):335-45.
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Factors determining specificity of signal transduction by G-protein-coupled receptors. Regulation of signal transfer from receptor to G-protein. J Biol Chem. 1995 Jun 23; 270(25):15269-76.
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Characterization of [125I](R)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino] tetralin binding to dopamine D3 receptors in rat olfactory tubercle. J Pharmacol Exp Ther. 1994 Feb; 268(2):935-42.
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Differential effects of cytosolic modulators of fluoride-stimulated adenylate cyclase activity in striatum and cerebral cortex. Alcohol Drug Res. 1985-1986; 6(6):379-86.
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Desensitization of beta-adrenergic receptor-coupled adenylate cyclase activity. Differences following exposure of cells to two full agonists. Biochem Pharmacol. 1984 Nov 15; 33(22):3579-84.
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Effects of guanine nucleotides and Mg on human erythrocyte Ni and Ns, the regulatory components of adenylyl cyclase. J Biol Chem. 1984 Sep 25; 259(18):11408-18.
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Identification of a gamma subunit associated with the adenylyl cyclase regulatory proteins Ns and Ni. J Biol Chem. 1984 Feb 25; 259(4):2039-42.
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Mechanisms in the vectorial receptor-adenylate cyclase signal transduction. Adv Cyclic Nucleotide Protein Phosphorylation Res. 1984; 17:111-25.