Heterotrimeric GTP-Binding Proteins
"Heterotrimeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.
| Descriptor ID |
D020962
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| MeSH Number(s) |
D08.811.277.040.330.300.200 D12.644.360.360 D12.776.157.325.332 D12.776.476.375 D12.776.543.325
|
| Concept/Terms |
Heterotrimeric GTP-Binding Proteins- Heterotrimeric GTP-Binding Proteins
- GTP-Binding Proteins, Heterotrimeric
- Heterotrimeric GTP Binding Proteins
- Heterotrimeric G-Proteins
- G-Proteins, Heterotrimeric
- Heterotrimeric G Proteins
|
Below are MeSH descriptors whose meaning is more general than "Heterotrimeric GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Heterotrimeric GTP-Binding Proteins".
This graph shows the total number of publications written about "Heterotrimeric GTP-Binding Proteins" by people in this website by year, and whether "Heterotrimeric GTP-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 5 | 0 | 5 |
| 2003 | 4 | 2 | 6 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heterotrimeric GTP-Binding Proteins" by people in Profiles.
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Structural basis for GPCR-independent activation of heterotrimeric Gi proteins. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16394-16403.
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Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain. Cell Signal. 2018 Jan; 42:281-291.
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Regulation of Chemokine Signal Integration by Activator of G-Protein Signaling 4 (AGS4). J Pharmacol Exp Ther. 2017 03; 360(3):424-433.
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Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif. Acta Physiol (Oxf). 2012 Feb; 204(2):202-18.
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Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol Rev. 2010 Jun; 62(2):305-30.
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Angiotensin II-induced cyclooxygenase 2 expression in rat aorta vascular smooth muscle cells does not require heterotrimeric G protein activation. J Pharmacol Exp Ther. 2009 Jul; 330(1):118-24.
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Heptahelical terpsichory. Who calls the tune? J Recept Signal Transduct Res. 2008; 28(1-2):39-58.
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Sequence dependence and differential expression of Ggamma5 subunit isoforms of the heterotrimeric G proteins variably processed after prenylation in mammalian cells. J Biol Chem. 2007 May 11; 282(19):14038-47.
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Transmembrane signaling by G protein-coupled receptors. Methods Mol Biol. 2006; 332:3-49.
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G Protein betagamma dimer formation: Gbeta and Ggamma differentially determine efficiency of in vitro dimer formation. Biochemistry. 2005 Sep 06; 44(35):11882-90.