RNA-Induced Silencing Complex
"RNA-Induced Silencing Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multicomponent, ribonucleoprotein complex comprised of one of the family of ARGONAUTE PROTEINS and the "guide strand" of the one of the 20- to 30-nucleotide small RNAs. RISC cleaves specific RNAs, which are targeted for degradation by homology to these small RNAs. Functions in regulating gene expression are determined by the specific argonaute protein and small RNA including siRNA (RNA, SMALL INTERFERING), miRNA (MICRORNA), or piRNA (PIWI-INTERACTING RNA).
| Descriptor ID |
D034743
|
| MeSH Number(s) |
D08.811.277.352.355.350.810 D08.811.277.352.700.350.810 D12.776.157.725.500.906 D12.776.664.962.500.906
|
| Concept/Terms |
RNA-Induced Silencing Complex- RNA-Induced Silencing Complex
- Complex, RNA-Induced Silencing
- RNA Induced Silencing Complex
- Silencing Complex, RNA-Induced
- RISC Multicomponent Nuclease
- Multicomponent Nuclease, RISC
- Nuclease, RISC Multicomponent
|
Below are MeSH descriptors whose meaning is more general than "RNA-Induced Silencing Complex".
Below are MeSH descriptors whose meaning is more specific than "RNA-Induced Silencing Complex".
This graph shows the total number of publications written about "RNA-Induced Silencing Complex" by people in this website by year, and whether "RNA-Induced Silencing Complex" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "RNA-Induced Silencing Complex" by people in Profiles.
-
Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling. J Cell Biol. 2017 10 02; 216(10):3073-3085.
-
Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation. Nat Genet. 2011 Feb; 43(2):153-8.
-
Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila. Nat Struct Mol Biol. 2010 May; 17(5):547-54.