Insulin-Like Growth Factor I
"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
| Descriptor ID |
D007334
|
| MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
|
| Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in this website by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 1 | 1 | 2 |
| 1996 | 2 | 2 | 4 |
| 1997 | 1 | 1 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 3 | 1 | 4 |
| 2001 | 2 | 2 | 4 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 5 | 1 | 6 |
| 2005 | 4 | 2 | 6 |
| 2006 | 4 | 1 | 5 |
| 2007 | 3 | 2 | 5 |
| 2008 | 3 | 2 | 5 |
| 2009 | 0 | 2 | 2 |
| 2010 | 2 | 3 | 5 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 3 | 4 |
| 2013 | 3 | 1 | 4 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 3 | 4 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles.
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IGF-dependent dynamic modulation of a protease cleavage site in the intrinsically disordered linker domain of human IGFBP2. Proteins. 2022 09; 90(9):1732-1743.
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Prominence of IL6, IGF, TLR, and Bioenergetics Pathway Perturbation in Lung Tissues of Scleroderma Patients With Pulmonary Fibrosis. Front Immunol. 2020; 11:383.
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Adipose stem cells from chronic pancreatitis patients improve mouse and human islet survival and function. Stem Cell Res Ther. 2017 08 30; 8(1):192.
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Commensal Gut Microbiota Immunomodulatory Actions in Bone Marrow and Liver have Catabolic Effects on Skeletal Homeostasis in Health. Sci Rep. 2017 07 18; 7(1):5747.
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Embryonic-only arsenic exposure in killifish (Fundulus heteroclitus) reduces growth and alters muscle IGF levels one year later. Aquat Toxicol. 2017 May; 186:1-10.
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Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue. J Hematol Oncol. 2017 01 11; 10(1):14.
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Effects of In Utero Thyroxine Exposure on Murine Cranial Suture Growth. PLoS One. 2016; 11(12):e0167805.
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In ovo treatment with an estrogen receptor alpha selective agonist causes precocious development of the female reproductive tract of the American alligator (Alligator mississippiensis). Gen Comp Endocrinol. 2016 11 01; 238:96-104.
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The adipokine leptin mediates muscle- and liver-derived IGF-1 in aged mice. Exp Gerontol. 2015 Oct; 70:92-6.
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The aromatic amino acid tryptophan stimulates skeletal muscle IGF1/p70s6k/mTor signaling in vivo and the expression of myogenic genes in vitro. Nutrition. 2015 Jul-Aug; 31(7-8):1018-24.