8-Hydroxy-2-(di-n-propylamino)tetralin
"8-Hydroxy-2-(di-n-propylamino)tetralin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
| Descriptor ID |
D017371
|
| MeSH Number(s) |
D02.455.426.559.847.638.960.400 D04.615.638.960.400
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "8-Hydroxy-2-(di-n-propylamino)tetralin".
Below are MeSH descriptors whose meaning is more specific than "8-Hydroxy-2-(di-n-propylamino)tetralin".
This graph shows the total number of publications written about "8-Hydroxy-2-(di-n-propylamino)tetralin" by people in this website by year, and whether "8-Hydroxy-2-(di-n-propylamino)tetralin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
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Below are the most recent publications written about "8-Hydroxy-2-(di-n-propylamino)tetralin" by people in Profiles.
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Serotonin 5-HT1A receptor stimulates c-Jun N-terminal kinase and induces apoptosis in Chinese hamster ovary fibroblasts. Biochim Biophys Acta. 2007 Mar; 1773(3):391-9.
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Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor. J Pharmacol Exp Ther. 2007 Jan; 320(1):314-22.
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Prenatal stress influences 8-OH-DPAT modulated startle responding and [3H]-8-OH-DPAT binding in rats. Pharmacol Biochem Behav. 2005 Jul; 81(3):601-7.
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Dissociable roles for the dorsal and median raph? in the facilitatory effect of 5-HT1A receptor stimulation upon cocaine-induced locomotion and sensitization. Neuropsychopharmacology. 2004 Sep; 29(9):1675-87.
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8OH-DPAT-Induced ocular hypotension: sites and mechanisms of action. Exp Eye Res. 1999 Aug; 69(2):227-38.
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5-HT1A receptor activates Na+/H+ exchange in CHO-K1 cells through Gialpha2 and Gialpha3. J Biol Chem. 1997 Mar 21; 272(12):7770-6.
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Agonist-induced desensitization and phosphorylation of human 5-HT1A receptor expressed in Sf9 insect cells. Biochemistry. 1995 Sep 19; 34(37):11954-62.
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Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits. J Biol Chem. 1995 Aug 04; 270(31):18691-9.
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Detection of the 5-HT1A receptor and 5-HT1A receptor mRNA in the rat bowel and pancreas: comparison with 5-HT1P receptors. J Comp Neurol. 1993 Jan 08; 327(2):233-50.