Nuclear Receptor Subfamily 1, Group F, Member 3
"Nuclear Receptor Subfamily 1, Group F, Member 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An orphan nuclear receptor found in the THYMUS where it plays a role in regulating the development and maturation of thymocytes. An isoform of this protein, referred to as RORgammaT, is produced by an alternatively transcribed mRNA.
Descriptor ID |
D057132
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MeSH Number(s) |
D12.776.260.643.182 D12.776.826.209.182
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Concept/Terms |
Nuclear Receptor Subfamily 1, Group F, Member 3- Nuclear Receptor Subfamily 1, Group F, Member 3
- Nuclear Receptor RZR-gamma
- Nuclear Receptor RZR gamma
- Receptor RZR-gamma, Nuclear
- ROR-gamma
- Orphan Nuclear Receptor ROR-gamma
- Orphan Nuclear Receptor ROR gamma
- RAR-related Orphan Receptor C
- RAR related Orphan Receptor C
- ROR-C Receptors
- ROR C Receptors
- Nuclear Receptor NR1F3
- Receptor NR1F3, Nuclear
- Orphan Nuclear Receptor NR1F3
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 1, Group F, Member 3".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 1, Group F, Member 3".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 1, Group F, Member 3" by people in this website by year, and whether "Nuclear Receptor Subfamily 1, Group F, Member 3" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 2 | 2 |
2012 | 1 | 2 | 3 |
2017 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Subfamily 1, Group F, Member 3" by people in Profiles.
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Discovery of LYC-55716: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor-? (ROR?) Agonist for Use in Treating Cancer. J Med Chem. 2021 09 23; 64(18):13410-13428.
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In Vitro Priming of Adoptively Transferred T Cells with a ROR? Agonist Confers Durable Memory and Stemness In Vivo. Cancer Res. 2018 07 15; 78(14):3888-3898.
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Evolution of T Cell Responses during Measles Virus Infection and RNA Clearance. Sci Rep. 2017 09 13; 7(1):11474.
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Expression of ROR?t marks a pathogenic regulatory T cell subset in human colon cancer. Sci Transl Med. 2012 Dec 12; 4(164):164ra159.
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Glatiramer acetate biases dendritic cells towards an anti-inflammatory phenotype by modulating OPN, IL-17, and ROR?t responses and by increasing IL-10 production in experimental allergic encephalomyelitis. J Neuroimmunol. 2013 Jan 15; 254(1-2):117-24.
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Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunol. 2012 Nov; 5(6):646-57.
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The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells. Sci Transl Med. 2010 Oct 27; 2(55):55ra78.
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S-nitrosoglutathione a physiologic nitric oxide carrier attenuates experimental autoimmune encephalomyelitis. J Neuroimmune Pharmacol. 2010 Jun; 5(2):240-51.