Nuclear Receptor Subfamily 1, Group D, Member 1
"Nuclear Receptor Subfamily 1, Group D, Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.
| Descriptor ID |
D056953
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| MeSH Number(s) |
D12.776.189.300 D12.776.260.643.080 D12.776.826.209.080
|
| Concept/Terms |
Nuclear Receptor Subfamily 1, Group D, Member 1- Nuclear Receptor Subfamily 1, Group D, Member 1
- Rev-erb-alpha Nuclear Receptors
- Nuclear Receptors, Rev-erb-alpha
- Rev erb alpha Nuclear Receptors
- V-erbA-Related Protein EAR-1
- V erbA Related Protein EAR 1
- Nuclear Receptor NR1D1
- NR1D1, Nuclear Receptor
- Receptor NR1D1, Nuclear
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 1, Group D, Member 1".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 1, Group D, Member 1".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 1, Group D, Member 1" by people in this website by year, and whether "Nuclear Receptor Subfamily 1, Group D, Member 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Subfamily 1, Group D, Member 1" by people in Profiles.
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NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons. FASEB J. 2022 04; 36(4):e22262.
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An RNA interference screen identifies metabolic regulators NR1D1 and PBP as novel survival factors for breast cancer cells with the ERBB2 signature. Cancer Res. 2010 Mar 01; 70(5):1783-92.