"Receptors, CCR5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expressed at high levels in T-LYMPHOCYTES; B-LYMPHOCYTES; MACROPHAGES; MAST CELLS; and NK CELLS. The CCR5 receptor is used by the HUMAN IMMUNODEFICIENCY VIRUS to infect cells.
| Descriptor ID |
D019713
|
| MeSH Number(s) |
D12.776.543.750.695.160.150.500 D12.776.543.750.705.852.125.150.500 D12.776.543.750.830.700.605
|
| Concept/Terms |
Receptors, CCR5- Receptors, CCR5
- CC-CKR5
- CCR5 Receptor
- Receptor, CCR5
- CCR5 Receptors
- Antigens, CD195
- CKR5 Receptors
- Receptors, CKR5
- CD195 Antigens
- CC Chemokine Receptor 5
|
Below are MeSH descriptors whose meaning is more general than "Receptors, CCR5".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Chemokine [D12.776.543.750.695.160]
- Receptors, CCR [D12.776.543.750.695.160.150]
- Receptors, CCR5 [D12.776.543.750.695.160.150.500]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Chemokine [D12.776.543.750.705.852.125]
- Receptors, CCR [D12.776.543.750.705.852.125.150]
- Receptors, CCR5 [D12.776.543.750.705.852.125.150.500]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, HIV [D12.776.543.750.830.700]
- Receptors, CCR5 [D12.776.543.750.830.700.605]
Below are MeSH descriptors whose meaning is more specific than "Receptors, CCR5".
This graph shows the total number of publications written about "Receptors, CCR5" by people in this website by year, and whether "Receptors, CCR5" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptors, CCR5" by people in Profiles.
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CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV. J Am Heart Assoc. 2014 Apr 02; 3(2):e000874.
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A quantitative increase in regulatory T cells controls development of vitiligo. J Invest Dermatol. 2014 May; 134(5):1285-1294.
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Mucosal transmissibility, disease induction and coreceptor switching of R5 SHIVSF162P3N molecular clones in rhesus macaques. Retrovirology. 2013 Jan 31; 10:9.
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Adoption of an "open" envelope conformation facilitating CD4 binding and structural remodeling precedes coreceptor switch in R5 SHIV-infected macaques. PLoS One. 2011; 6(7):e21350.
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V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies. PLoS Pathog. 2007 Aug 24; 3(8):e117.
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Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry. J Immunol. 1998 Apr 15; 160(8):3933-41.
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Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J Immunol. 1998 Apr 15; 160(8):4018-25.