"Twist-Related Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that was originally identified in DROSOPHILA as essential for proper gastrulation and MESODERM formation. It plays an important role in EMBRYONIC DEVELOPMENT and CELL DIFFERENTIATION of MUSCLE CELLS, and is found in a wide variety of organisms.
Descriptor ID |
D051879
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MeSH Number(s) |
D12.776.260.103.906.250 D12.776.930.125.906.250
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Concept/Terms |
Twist-Related Protein 1- Twist-Related Protein 1
- Twist Related Protein 1
- Twist Transcription Factor
- Transcription Factor, Twist
- Twist Protein
- TWIST1 Protein
- Twist Family Bhlh Transcription Factor 1
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Below are MeSH descriptors whose meaning is more general than "Twist-Related Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Twist-Related Protein 1".
This graph shows the total number of publications written about "Twist-Related Protein 1" by people in this website by year, and whether "Twist-Related Protein 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 2 | 2 |
2004 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 1 | 2 |
2013 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Twist-Related Protein 1" by people in Profiles.
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ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions. J Cell Sci. 2017 Jun 15; 130(12):2036-2048.
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Effects of thyroxine exposure on the Twist 1 +/- phenotype: A test of gene-environment interaction modeling for craniosynostosis. Birth Defects Res A Clin Mol Teratol. 2016 Oct; 106(10):803-813.
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Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. Arthritis Rheumatol. 2016 Jan; 68(1):210-7.
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Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironment. Cancer Res. 2013 Sep 01; 73(17):5347-59.
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Expression of epithelial-mesenchymal transition-inducing transcription factors in primary breast cancer: The effect of neoadjuvant therapy. Int J Cancer. 2012 Feb 15; 130(4):808-16.
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Twist1-induced invadopodia formation promotes tumor metastasis. Cancer Cell. 2011 Mar 08; 19(3):372-86.
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Epithelial-to-mesenchymal transition promotes tubulin detyrosination and microtentacles that enhance endothelial engagement. Cancer Res. 2010 Oct 15; 70(20):8127-37.
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BMP-2 induces cell migration and periostin expression during atrioventricular valvulogenesis. Dev Biol. 2008 Mar 15; 315(2):383-96.
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Very high frequency of hypermethylated genes in breast cancer metastasis to the bone, brain, and lung. Clin Cancer Res. 2004 May 01; 10(9):3104-9.
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DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma. Int J Cancer. 2003 Dec 20; 107(6):970-5.