"Syndecan-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndecan that is predominantly expressed during EMBRYONIC DEVELOPMENT. It may play a role in mediating cellular interactions with the EXTRACELLULAR MATRIX and may modulate the signaling activity of certain INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS.
| Descriptor ID |
D053669
|
| MeSH Number(s) |
D12.776.395.550.847.200 D12.776.395.650.350.500.200 D12.776.543.550.847.200
|
| Concept/Terms |
Syndecan-2- Syndecan-2
- Syndecan 2
- Fibroglycan
- Heparan Sulfate Proteoglycan Core Protein
|
Below are MeSH descriptors whose meaning is more general than "Syndecan-2".
Below are MeSH descriptors whose meaning is more specific than "Syndecan-2".
This graph shows the total number of publications written about "Syndecan-2" by people in this website by year, and whether "Syndecan-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Syndecan-2" by people in Profiles.
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Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-? receptor I internalization and inhibiting transforming growth factor-?1 signaling. Am J Respir Crit Care Med. 2013 Oct 01; 188(7):831-41.
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Syndecan-2 is a novel target of insulin-like growth factor binding protein-3 and is over-expressed in fibrosis. PLoS One. 2012; 7(8):e43049.