"Dynorphins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.
| Descriptor ID |
D004399
|
| MeSH Number(s) |
D12.644.400.575.180 D12.776.631.650.575.180
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Dynorphins".
Below are MeSH descriptors whose meaning is more specific than "Dynorphins".
This graph shows the total number of publications written about "Dynorphins" by people in this website by year, and whether "Dynorphins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 4 | 2 | 6 |
| 1995 | 5 | 1 | 6 |
| 1996 | 4 | 0 | 4 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 2 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 2 | 4 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 3 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dynorphins" by people in Profiles.
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Dynorphin/Kappa Opioid Receptor Activity Within the Extended Amygdala Contributes to Stress-Enhanced Alcohol Drinking in Mice. Biol Psychiatry. 2022 06 15; 91(12):1019-1028.
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Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice. Neuropsychopharmacology. 2019 05; 44(6):1084-1092.
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Contribution of Dynorphin and Orexin Neuropeptide Systems to the Motivational Effects of Alcohol. Handb Exp Pharmacol. 2018; 248:473-503.
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Role of the Dynorphin/Kappa Opioid Receptor System in the Motivational Effects of Ethanol. Alcohol Clin Exp Res. 2017 Aug; 41(8):1402-1418.
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Opioidergic projections to sleep-active neurons in the ventrolateral preoptic nucleus. Brain Res. 2008 Dec 15; 1245:96-107.
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Amphetamine-induced locomotion and gene expression are altered in BDNF heterozygous mice. Genes Brain Behav. 2008 Nov; 7(8):906-14.
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Genetic and early environmental contributions to alcohol's aversive and physiological effects. Pharmacol Biochem Behav. 2008 Nov; 91(1):134-9.
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Extracellular signal-regulated mitogen-activated protein kinase inhibitors decrease amphetamine-induced behavior and neuropeptide gene expression in the striatum. Neuroscience. 2006; 138(4):1289-98.
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Involvement of mesolimbic structures in short-term sodium depletion: in situ hybridization and ligand-binding analyses. Neuroendocrinology. 2003 Jun; 77(6):406-15.
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NK-1 receptor blockade decreases amphetamine-induced behavior and neuropeptide mRNA expression in the striatum. Brain Res. 2002 Mar 22; 931(1):41-9.