"Germinal Center" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T-LYMPHOCYTES, HELPER-INDUCER) are stimulated to generate memory cells.
| Descriptor ID |
D018858
|
| MeSH Number(s) |
A10.549.400.500 A15.382.520.604.412.500
|
| Concept/Terms |
Germinal Center- Germinal Center
- Center, Germinal
- Centers, Germinal
- Germinal Centers
|
Below are MeSH descriptors whose meaning is more general than "Germinal Center".
Below are MeSH descriptors whose meaning is more specific than "Germinal Center".
This graph shows the total number of publications written about "Germinal Center" by people in this website by year, and whether "Germinal Center" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Germinal Center" by people in Profiles.
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Systemic translocation of Staphylococcus drives autoantibody production in HIV disease. Microbiome. 2019 02 14; 7(1):25.
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MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice. Blood. 2018 04 26; 131(17):1974-1986.
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Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation. J Exp Med. 2014 Jan 13; 211(1):45-56.
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Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers. PLoS One. 2013; 8(3):e57785.
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Heterologous protein incites abnormal plasma cell accumulation and autoimmunity in MRL-MpJ mice. Autoimmunity. 2012 Jun; 45(4):279-89.
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Salivary glands act as mucosal inductive sites via the formation of ectopic germinal centers after site-restricted MCMV infection. FASEB J. 2011 May; 25(5):1680-96.
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The origin of anti-nuclear antibodies in bcl-2 transgenic mice. Int Immunol. 2000 Mar; 12(3):353-64.