"Protein Denaturation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.
| Descriptor ID |
D011489
|
| MeSH Number(s) |
E05.793.500 G01.154.651.750.500 G02.111.688.750.500
|
| Concept/Terms |
Protein Denaturation- Protein Denaturation
- Denaturation, Protein
- Denaturations, Protein
- Protein Denaturations
|
Below are MeSH descriptors whose meaning is more general than "Protein Denaturation".
Below are MeSH descriptors whose meaning is more specific than "Protein Denaturation".
This graph shows the total number of publications written about "Protein Denaturation" by people in this website by year, and whether "Protein Denaturation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 2 | 2 |
| 2014 | 0 | 3 | 3 |
| 2015 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Denaturation" by people in Profiles.
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A small-molecule screen reveals that HSP90? promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover. Development. 2017 05 15; 144(10):1764-1774.
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Mutations in the KDM5C ARID Domain and Their Plausible Association with Syndromic Claes-Jensen-Type Disease. Int J Mol Sci. 2015 Nov 13; 16(11):27270-87.
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Evaluation of the Effectiveness of Surfactants and Denaturants to Elute and Denature Adsorbed Protein on Different Surface Chemistries. Langmuir. 2015 Nov 03; 31(43):11814-24.
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The Langmuir isotherm: a commonly applied but misleading approach for the analysis of protein adsorption behavior. J Biomed Mater Res A. 2015 Mar; 103(3):949-58.
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Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation. Endocrinology. 2014 Mar; 155(3):818-28.
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Neomycin and pentagalloyl glucose enhanced cross-linking for elastin and glycosaminoglycans preservation in bioprosthetic heart valves. J Biomater Appl. 2014 Jan; 28(5):757-66.
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Metal retention in human transferrin: consequences of solvent composition in analytical sample preparation methods. Metallomics. 2011 Oct; 3(10):1027-34.
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Multifunctional nanoadditives for the thermodynamic and kinetic stabilization of enzymes. Nanoscale. 2011 Oct 05; 3(10):4085-7.
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Studying pressure denaturation of a protein by molecular dynamics simulations. Proteins. 2010 May 15; 78(7):1641-51.
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Calorimetric and spectroscopic studies of aminoglycoside binding to AT-rich DNA triple helices. Biochimie. 2010 May; 92(5):514-29.