Oncogene Proteins v-erbA

"Oncogene Proteins v-erbA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
Transforming proteins encoded by erbA oncogenes from the avian erythroblastosis virus. They are truncated versions of c-erbA, the thyroid hormone receptor (RECEPTORS, THYROID HORMONE) that have retained both the DNA-binding and hormone-binding domains. Mutations in the hormone-binding domains abolish the transcriptional activation function. v-erbA acts as a dominant repressor of c-erbA, inducing transformation by disinhibiting proliferation.


expand / collapse publications
This graph shows the total number of publications written about "Oncogene Proteins v-erbA" by people in this website by year, and whether "Oncogene Proteins v-erbA" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
_