Oncogene Protein p21(ras)
"Oncogene Protein p21(ras)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D015689
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| MeSH Number(s) |
D08.811.277.040.330.300.400.500.300 D12.644.360.525.500.300 D12.776.157.325.515.500.300 D12.776.476.525.500.300 D12.776.624.664.520.750.710 D12.776.964.700.750.710 D12.776.964.775.750.710
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| Concept/Terms |
Oncogene Protein p21(ras)- Oncogene Protein p21(ras)
- p21 Transforming Viral Protein
- p21 v-H-ras
- p21 v H ras
- v-H-ras, p21
- p21(v-H-ras)
- p21 v-Ki-ras
- p21 v Ki ras
- v-Ki-ras, p21
- p21 v-ras
- p21 v ras
- v-ras, p21
- ras Oncogene p21 Product
- ras Oncogene Product p21
- p21 v-Ha-ras
- p21 v Ha ras
- v-Ha-ras, p21
- p21(v-Ha-ras)
- p21(v-K-ras)
- ras Oncogene Protein p21
- p21(v-Ki-ras)
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Below are MeSH descriptors whose meaning is more general than "Oncogene Protein p21(ras)".
Below are MeSH descriptors whose meaning is more specific than "Oncogene Protein p21(ras)".
This graph shows the total number of publications written about "Oncogene Protein p21(ras)" by people in this website by year, and whether "Oncogene Protein p21(ras)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oncogene Protein p21(ras)" by people in Profiles.
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Intersectin scaffold proteins and their role in cell signaling and endocytosis. Biochim Biophys Acta Mol Cell Res. 2017 Jan; 1864(1):23-30.
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MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation. PLoS One. 2014; 9(6):e100693.
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Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors. Biochemistry. 2006 Dec 26; 45(51):15862-72.
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Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling. J Biol Chem. 1995 Jun 02; 270(22):12984-9.
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An enhancer element responsive to ras and fms signaling pathways is composed of two distinct nuclear factor binding sites. Mol Endocrinol. 1992 Jul; 6(7):1051-60.
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A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors. Mol Cell Biol. 1991 Oct; 11(10):4830-8.
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ras oncogene activation of a VL30 transcriptional element is linked to transformation. Mol Cell Biol. 1990 Jan; 10(1):1-9.