"Baclofen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
| Descriptor ID |
D001418
|
| MeSH Number(s) |
D02.241.081.114.500.350.100
|
| Concept/Terms |
Baclofen- Baclofen
- Baclophen
- PCP-GABA
- beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
- Chlorophenyl GABA
- GABA, Chlorophenyl
- beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
Ba-34,647- Ba-34,647
- Ba34,647
- Ba-34647
- Ba34647
- CIBA-34,647-BA
- CIBA34,647BA
|
Below are MeSH descriptors whose meaning is more general than "Baclofen".
Below are MeSH descriptors whose meaning is more specific than "Baclofen".
This graph shows the total number of publications written about "Baclofen" by people in this website by year, and whether "Baclofen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Baclofen" by people in Profiles.
-
Baclofen Pump Use: Complications After Growth-friendly Instrumentation for Early-onset Scoliosis. J Pediatr Orthop. 2022 Feb 01; 42(2):77-82.
-
Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn. N Engl J Med. 2019 10 17; 381(16):1513-1523.
-
Baclofen-induced neurotoxicity in patients with compromised renal function: Review. Int J Clin Pharmacol Ther. 2018 Oct; 56(10):467-475.
-
Olanzapine and baclofen for the treatment of intractable hiccups. Pharmacotherapy. 2014 Jan; 34(1):e4-8.
-
Inactivation of the bed nucleus of the stria terminalis in an animal model of relapse: effects on conditioned cue-induced reinstatement and its enhancement by yohimbine. Psychopharmacology (Berl). 2011 Jan; 213(1):19-27.
-
A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA. Support Care Cancer. 2011 Jun; 19(6):833-41.
-
The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration. Learn Mem. 2010 Apr; 17(4):168-75.
-
Arbaclofen placarbil decreases postprandial reflux in patients with gastroesophageal reflux disease. Am J Gastroenterol. 2010 Jun; 105(6):1266-75.
-
Clinical and neurophysiologic assessment of strength and spasticity during intrathecal baclofen titration in incomplete spinal cord injury: single-subject design. J Spinal Cord Med. 2009; 32(2):183-90.
-
Intracerebral baclofen administration decreases amphetamine-induced behavior and neuropeptide gene expression in the striatum. Neuropsychopharmacology. 2005 May; 30(5):880-90.