"Toll-Like Receptor 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that binds DOUBLE-STRANDED RNA. It mediates cellular responses to certain viral pathogens.
Descriptor ID |
D051196
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MeSH Number(s) |
D12.776.543.750.705.910.500.300
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 3".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 3".
This graph shows the total number of publications written about "Toll-Like Receptor 3" by people in this website by year, and whether "Toll-Like Receptor 3" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2009 | 1 | 2 | 3 |
2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Toll-Like Receptor 3" by people in Profiles.
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Estrogen receptor alpha modulates mesangial cell responses to toll-like receptor ligands. Am J Med Sci. 2014 Dec; 348(6):492-500.
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Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection. Am J Physiol Lung Cell Mol Physiol. 2009 Jul; 297(1):L64-72.
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Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C). J Immunol. 2009 Feb 15; 182(4):2030-40.
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Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. Circ Res. 2009 Feb 27; 104(4):455-65.
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The TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into na?ve recipient mice. Vaccine. 2009 Jan 22; 27(4):549-57.
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Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells. J Immunother. 2007 Jan; 30(1):40-53.
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The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu. Vaccine. 2006 Jun 12; 24(24):5119-32.
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Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity. J Immunother. 2005 May-Jun; 28(3):220-8.