"Toll-Like Receptor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
| Descriptor ID |
D051197
|
| MeSH Number(s) |
D12.776.543.750.705.910.500.400
|
| Concept/Terms |
Toll-Like Receptor 4- Toll-Like Receptor 4
- Toll Like Receptor 4
- Toll-4 Receptor
- Toll 4 Receptor
- TLR4 Receptor
- Receptor, TLR4
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 4".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 4".
This graph shows the total number of publications written about "Toll-Like Receptor 4" by people in this website by year, and whether "Toll-Like Receptor 4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 3 | 2 | 5 |
| 2008 | 0 | 2 | 2 |
| 2009 | 4 | 0 | 4 |
| 2010 | 3 | 1 | 4 |
| 2011 | 5 | 3 | 8 |
| 2012 | 3 | 2 | 5 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 4 | 5 |
| 2015 | 9 | 4 | 13 |
| 2016 | 2 | 1 | 3 |
| 2017 | 2 | 1 | 3 |
| 2018 | 4 | 2 | 6 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Toll-Like Receptor 4" by people in Profiles.
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The role of neuraminidase in TLR4-MAPK signalling and the release of cytokines by lupus serum-stimulated mesangial cells. Immunology. 2021 04; 162(4):418-433.
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Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis. J Neuroinflammation. 2020 Jul 04; 17(1):201.
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Peroxisomal footprint in the pathogenesis of nonalcoholic steatohepatitis. Ann Hepatol. 2020 Sep - Oct; 19(5):466-471.
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Enhanced Signal Amplification in a Toll-like Receptor-4 Biosensor Utilizing Ferrocene-Terminated Mixed Monolayers. ACS Sens. 2019 01 25; 4(1):143-151.
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Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. Eur J Pharmacol. 2018 Dec 15; 841:33-48.
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Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4. Mol Neurobiol. 2019 Mar; 56(3):1607-1617.
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The Pathologic Role of Toll-Like Receptor 4 in Prostate Cancer. Front Immunol. 2018; 9:1188.
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The innate immune response to ischemic injury: a multiscale modeling perspective. BMC Syst Biol. 2018 04 10; 12(1):50.
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The Synergy between Palmitate and TNF-a for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation. J Immunol. 2018 05 15; 200(10):3599-3611.
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Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking. Brain Behav Immun. 2018 Jan; 67:130-138.