"Aquaporin 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.
| Descriptor ID |
D051399
|
| MeSH Number(s) |
D12.776.157.530.400.500.040.437 D12.776.543.550.450.730.040.437 D12.776.543.585.400.730.040.530
|
| Concept/Terms |
Aquaporin 2- Aquaporin 2
- AQP2 Protein
- Water Channel Of Collecting Duct
- Aquaporin-2
- Aquaporin-CD
- Aquaporin CD
|
Below are MeSH descriptors whose meaning is more general than "Aquaporin 2".
Below are MeSH descriptors whose meaning is more specific than "Aquaporin 2".
This graph shows the total number of publications written about "Aquaporin 2" by people in this website by year, and whether "Aquaporin 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aquaporin 2" by people in Profiles.
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Impaired epithelial Na+ channel activity contributes to cystogenesis and development of autosomal recessive polycystic kidney disease in PCK rats. Pediatr Res. 2015 Jan; 77(1-1):64-9.
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Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors. Am J Physiol Renal Physiol. 2012 Apr 01; 302(7):F801-8.
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N-methyl-D-aspartate receptor subunit NR3a expression and function in principal cells of the collecting duct. Am J Physiol Renal Physiol. 2011 Jul; 301(1):F44-54.