"Galactosylceramides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cerebrosides which contain as their polar head group a galactose moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in beta-galactosidase, is the cause of galactosylceramide lipidosis or globoid cell leukodystrophy.
| Descriptor ID |
D005699
|
| MeSH Number(s) |
D02.065.313.250.450 D09.400.410.420.525.200.250.450 D10.390.470.675.200.250.450 D10.570.877.360.612.200.250.450
|
| Concept/Terms |
Galactosylceramides- Galactosylceramides
- Galactosyl Ceramides
- Ceramides, Galactosyl
- Galactocerebrosides
|
Below are MeSH descriptors whose meaning is more general than "Galactosylceramides".
Below are MeSH descriptors whose meaning is more specific than "Galactosylceramides".
This graph shows the total number of publications written about "Galactosylceramides" by people in this website by year, and whether "Galactosylceramides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Galactosylceramides" by people in Profiles.
-
Invariant natural killer T cells and their ligands: focus on multiple sclerosis. Immunology. 2015 Aug; 145(4):468-75.
-
Invariant Natural Killer T-cell anergy to endogenous myelin acetyl-glycolipids in multiple sclerosis. J Neuroimmunol. 2013 Jun 15; 259(1-2):1-7.
-
Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: implication for Krabbe disease. Brain Res. 2013 May 01; 1508:44-52.
-
Novel myelin penta- and hexa-acetyl-galactosyl-ceramides: structural characterization and immunoreactivity in cerebrospinal fluid. J Lipid Res. 2010 Jun; 51(6):1394-406.
-
T-cells expressing natural killer (NK) receptors are altered in multiple sclerosis and responses to alpha-galactosylceramide are impaired. J Neurol Sci. 2008 Dec 15; 275(1-2):22-8.
-
Characterization of novel myelin components 3-O-acetyl-sphingosine galactosylceramides by electrospray ionization Q-TOF MS and MS/CID-MS of Li+ adducts. J Mass Spectrom. 2007 May; 42(5):598-620.
-
alpha-Galactosylceramide and novel synthetic glycolipids directly induce the innate host defense pathway and have direct activity against hepatitis B and C viruses. Antimicrob Agents Chemother. 2004 Jun; 48(6):2085-90.
-
Increased calpain expression in activated glial and inflammatory cells in experimental allergic encephalomyelitis. Proc Natl Acad Sci U S A. 1998 May 12; 95(10):5768-72.
-
Regulation of the calcium-activated neutral proteinase (CANP) of bovine brain by myelin lipids. Biochim Biophys Acta. 1990 Apr 19; 1038(2):195-8.