"Cimetidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
| Descriptor ID |
D002927
|
| MeSH Number(s) |
D02.078.370.200 D03.383.129.308.130
|
| Concept/Terms |
Cimetidine- Cimetidine
- N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine
SK&F-92334- SK&F-92334
- SK&F 92334
- SK&F92334
- SKF-92334
- SKF 92334
- SKF92334
|
Below are MeSH descriptors whose meaning is more general than "Cimetidine".
Below are MeSH descriptors whose meaning is more specific than "Cimetidine".
This graph shows the total number of publications written about "Cimetidine" by people in this website by year, and whether "Cimetidine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cimetidine" by people in Profiles.
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Inhibition of human gastric H(+)-K(+)-ATPase alpha-subunit gene expression by Helicobacter pylori. Am J Physiol Gastrointest Liver Physiol. 2000 Jun; 278(6):G981-91.
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A prospective randomized comparative trial showing that omeprazole prevents rebleeding in patients with bleeding peptic ulcers after successful endoscopic therapy. Gastrointest Endosc. 1999 Aug; 50(2):292-3.
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Control of gastric acid with high dose H2-receptor antagonists after omeprazole failure: report of two cases. Am J Gastroenterol. 1995 Oct; 90(10):1874-7.
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Immunological localization of an 80-kDa phosphoprotein to the apical membrane of gastric parietal cells. Am J Physiol. 1989 Jun; 256(6 Pt 1):G1082-9.
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Primary culture of secretagogue-responsive parietal cells from rabbit gastric mucosa. Am J Physiol. 1989 Jan; 256(1 Pt 1):G254-63.
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Long-term therapy for chronic gastroesophageal reflux. Arch Intern Med. 1987 Oct; 147(10):1701-2.
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Comparison of potential cytoprotective action of sucralfate and cimetidine. Studies with experimental feline esophagitis. Am J Med. 1987 Sep 28; 83(3B):56-60.
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Effects of antireflux therapies on salivary function in normal humans. Dig Dis Sci. 1987 Jun; 32(6):603-8.
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Histamine H2-receptor involvement in the regulation of gastric emptying. Am J Physiol. 1986 Feb; 250(2 Pt 1):G244-7.
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Medical therapy for reflux esophagitis: 1986 and beyond. Ann Intern Med. 1986 Jan; 104(1):112-4.