"Immunophilins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them.
| Descriptor ID |
D020104
|
| MeSH Number(s) |
D08.811.399.325.500.400 D12.776.543.750.705.400 D12.776.827.275
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Immunophilins".
Below are MeSH descriptors whose meaning is more specific than "Immunophilins".
This graph shows the total number of publications written about "Immunophilins" by people in this website by year, and whether "Immunophilins" was a major or minor topic of these publications.
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Below are the most recent publications written about "Immunophilins" by people in Profiles.
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A novel WISp39 protein links Hsp90 and p21 stability to the G2/M checkpoint. Cancer Biol Ther. 2005 Apr; 4(4):376-8.