"Cyclophilins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of peptidyl-prolyl cis-trans isomerases that bind to CYCLOSPORINS and regulate the IMMUNE SYSTEM. EC 5.2.1.-
| Descriptor ID |
D021983
|
| MeSH Number(s) |
D08.811.399.325.500.400.300 D12.776.543.750.705.400.300 D12.776.827.275.300
|
| Concept/Terms |
Cyclophilins- Cyclophilins
- Cyclosporin-Binding Proteins
- Cyclosporin Binding Proteins
- Proteins, Cyclosporin-Binding
- Cyclophilin
- Cyclosporin-Binding Protein
- Cyclosporin Binding Protein
- Protein, Cyclosporin-Binding
|
Below are MeSH descriptors whose meaning is more general than "Cyclophilins".
Below are MeSH descriptors whose meaning is more specific than "Cyclophilins".
This graph shows the total number of publications written about "Cyclophilins" by people in this website by year, and whether "Cyclophilins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclophilins" by people in Profiles.
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Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease. Antioxid Redox Signal. 2012 May 01; 16(9):855-68.
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Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury. Free Radic Res. 2011 Feb; 45(2):156-64.
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Long-chain ceramide is a potent inhibitor of the mitochondrial permeability transition pore. J Biol Chem. 2008 Sep 05; 283(36):24707-17.
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Cyclophilin D as a drug target. Curr Med Chem. 2003 Aug; 10(16):1485-506.
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Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? FEBS Lett. 2002 Feb 13; 512(1-3):1-7.