"Thrombospondin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumor growth and metastasis.
| Descriptor ID |
D019700
|
| MeSH Number(s) |
D12.776.395.550.895.800 D12.776.543.550.895.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thrombospondin 1".
Below are MeSH descriptors whose meaning is more specific than "Thrombospondin 1".
This graph shows the total number of publications written about "Thrombospondin 1" by people in this website by year, and whether "Thrombospondin 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thrombospondin 1" by people in Profiles.
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The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGF?-induced pulmonary fibrosis. Br J Pharmacol. 2015 Aug; 172(16):4173-88.