"Substance P" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
| Descriptor ID |
D013373
|
| MeSH Number(s) |
D12.644.276.812.900.866 D12.644.400.800.750 D12.644.456.800.866 D12.776.467.812.900.866 D12.776.631.650.800.750 D23.469.050.375.850.890 D23.529.812.900.866
|
| Concept/Terms |
Substance P- Substance P
- Euler-Gaddum Substance P
- Euler Gaddum Substance P
- Substance P, Euler-Gaddum
- SP(1-11)
|
Below are MeSH descriptors whose meaning is more general than "Substance P".
Below are MeSH descriptors whose meaning is more specific than "Substance P".
This graph shows the total number of publications written about "Substance P" by people in this website by year, and whether "Substance P" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 0 | 3 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 2 | 1 | 3 |
| 2005 | 2 | 1 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Substance P" by people in Profiles.
-
Inhibition of MRGPRX2 but not FceRI or MrgprB2-mediated mast cell degranulation by a small molecule inverse receptor agonist. Front Immunol. 2022; 13:1033794.
-
Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice. Am J Physiol Gastrointest Liver Physiol. 2011 Aug; 301(2):G297-305.
-
Co-localization of GABA with other neuroactive substances in the basal ganglia. Prog Brain Res. 2007; 160:273-84.
-
Anti-inflammatory effects of 4-phenyl-3-butenoic acid and 5-(acetylamino)-4-oxo-6-phenyl-2-hexenoic acid methyl ester, potential inhibitors of neuropeptide bioactivation. J Pharmacol Exp Ther. 2007 Mar; 320(3):1171-7.
-
Increased substance P content in nerve fibers associated with mesenteric veins from deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Regul Pept. 2006 Jan 15; 133(1-3):97-104.
-
Surface CD88 functionally distinguishes the MCTC from the MCT type of human lung mast cell. J Allergy Clin Immunol. 2005 Jun; 115(6):1162-8.
-
Calcitonin gene-related peptide and substance P contribute to reduced blood pressure in sympathectomized rats. Am J Physiol Heart Circ Physiol. 2005 Sep; 289(3):H1169-75.
-
Role of sensory nervous system vasoactive peptides in hypertension. Braz J Med Biol Res. 2002 Sep; 35(9):1033-45.
-
NK-1 receptor blockade decreases amphetamine-induced behavior and neuropeptide mRNA expression in the striatum. Brain Res. 2002 Mar 22; 931(1):41-9.
-
Substance P in subtotal nephrectomy-salt hypertension. Hypertension. 2002 Feb; 39(2 Pt 2):389-93.