Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis.

Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis. Am J Pathol. 2013 Mar; 182(3):646-67.

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subject areas

Animals
Base Pairing
Biomarkers, Tumor
Cell Cycle
Cell Transformation, Neoplastic
Chromosomes, Mammalian
Comparative Genomic Hybridization
Disease Models, Animal
Disease Progression
DNA Copy Number Variations
Humans
Mice
Mice, Inbred C57BL
Mice, Transgenic
Nerve Sheath Neoplasms
Neuregulin-1
Neurofibroma
Neurofibromin 1
Peripheral Nervous System
ras Proteins
Signal Transduction

authors with profiles

Steven L. Carroll